Norepinephrine – Noradrenaline

What is Norepinephrine?

Norepinephrine, also called Noradrenaline, is a chemical that acts as both a neurotransmitter in the brain and a hormone in the body. It’s essential for helping you stay focused, alert, and attentive. It plays a big role in your body’s “fight-or-flight” response, increasing your heart rate and preparing you for action. A balanced level is key: too much can cause anxiety, and too little can lead to symptoms of depression.

Norepinephrine is a catecholamine and a monoamine neurotransmitter synthesized from the amino acid tyrosine via dopamine. It is critical for regulating the sleep-wake cycle, attention, learning, and helps maintain working memory. As a hormone released by the adrenal glands, it works to increase heart rate, elevate blood pressure, and mobilize energy stores as part of the body’s acute stress response. Tyrosine needs cofactors like folic acid (Vitamin B9), magnesium, and vitamin B12 to convert effectively to norepinephrine.

Supplements that Promote Norepinephrine

  1. Tyrosine (Precursor)
  2. Vitamin B6
  3. Vitamin B12
  4. Folic Acid (Vitamin B9)
  5. Magnesium
  6. Chromium
  7. Omega-3 Fatty Acids

Top Benefits of Norepinephrine

Evidence-Based Nutritional Research Sources for Norepinephrine:

  1. HealthPartners → Foods that can boost your mental health
  2. Neurotrack → Let’s Talk Neurotransmitters
  3. Mental Health → What is Noradrenaline? | Mental Health America
  4. EBSCO → Epinephrine and norepinephrine | Research Starters